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Other and unspecified disorders of skin and subcutaneous tissue

DOID EFO MESH SNOMED PheWeb

L12_SKINSUBCUTISNAS

skin disease: Any deviation from the normal structure or function of the skin or subcutaneous tissue that is manifested by a characteristic set of symptoms and signs.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 L98.80, L98.88, L98.9
Hospital discharge: ICD-9 7019X|7098|7099
Hospital discharge: ICD-8 70198|7090[8-9]
Hospital discharge: excluded ICD-9 7098A|7098B
Cause of death: ICD-10 L98.80, L98.88, L98.9
Cause of death: ICD-9 7019X|7098|7099
Cause of death: ICD-8 70198|7090[8-9]
Cause of death: excluded ICD-9 7098A|7098B

2 out of 7 registries used, show all original rules.

2008

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Check minimum number of events None

2008

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Include endpoints None

2008

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Remove individuals based on genotype QC

1950

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L12_SKINSUBCUTISNAS

Control definitions

Control exclude L12_OTHERSKINSUBCUTIS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 1950 1221 729
Unadjusted prevalence (%) 0.52 0.58 0.44
Mean age at first event (years) 52.31 49.94 56.28

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.73 [1.05, 2.86] 3.3e-2 195
15 years 0.01 1.02 [0.60, 1.72] 9.4e-1 81
5 years 0.00 2.39 [1.52, 3.75] 1.7e-4 55
1 year 0.00 5.23 [3.09, 8.84] 6.7e-10 23

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_SKINSUBCUTISNAS – Other and unspecified disorders of skin and subcutaneous tissue
GWS hits:

Survival analyses between endpoints

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Plot

before Other and unspecified disorders of skin and subcutaneous tissue
after Other and unspecified disorders of skin and subcutaneous tissue

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other and unspecified disorders of skin and subcutaneous tissue

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Endpoint not on priority list, no data to show.