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Psoriasis vulgaris

DOID EFO MESH SNOMED PheWeb

L12_PSORI_VULG

psoriasis: An autoimmune condition characterized by red, well-delineated plaques with silvery scales that are usually on the extensor surfaces and scalp. They can occasionally present with these manifestations: pustules; erythema and scaling in intertriginous areas, and erythroderma, that are often distributed on extensor surfaces and scalp.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 L40.0
Hospital discharge: ICD-9 6961A
Cause of death: ICD-10 L40.0
Cause of death: ICD-9 6961A
KELA reimbursements: KELA codes ANY
KELA reimbursements: ICD-10 L40.0

3 out of 7 registries used, show all original rules.

5977

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Check minimum number of events None

5977

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Include endpoints None

5977

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Remove individuals based on genotype QC

5759

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L12_PSORI_VULG

Control definitions

Control exclude L12_PAPULOSQUAMOUS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L40
Name in latin Psoriasis vulgaris

Summary Statistics

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Key figures

All Female Male
Number of individuals 5759 2739 3020
Unadjusted prevalence (%) 1.53 1.30 1.82
Mean age at first event (years) 51.05 49.18 52.74

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.16 [1.52, 3.06] 1.7e-5 542
15 years 0.01 1.65 [1.27, 2.15] 1.9e-4 272
5 years 0.00 2.58 [2.02, 3.29] 2.1e-14 130
1 year 0.00 3.16 [2.14, 4.68] 7.8e-9 30

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_PSORI_VULG – Psoriasis vulgaris
GWS hits: 25

Survival analyses between endpoints

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Plot

before Psoriasis vulgaris
after Psoriasis vulgaris

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Psoriasis vulgaris

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Endpoint not on priority list, no data to show.