Generalized pustular psoriasis

DOID EFO MESH PheWeb

L12_PSORI_PUSTGEN

impetigo herpetiformis: An impetigo that is characterized as a form of severe pustular psoriasis occurring in pregnancy.

Endpoint definition

↥

FinnGen phenotype data

392423 individuals

diagram downward connector

Apply sex-specific rule None

392423

diagram downward connector

Check conditions None

392423

diagram downward connector

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 L40.1

Hospital discharge: ICD-9 6961B

Hospital discharge: ICD-8 69610

Cause of death: ICD-10 L40.1

Cause of death: ICD-9 6961B

Cause of death: ICD-8 69610

2 out of 7 registries used, show all original rules.

92

diagram downward connector

Check minimum number of events None

92

diagram downward connector

Include endpoints None

92

diagram downward connector

diagram downward connector

Remove individuals based on genotype QC

89

diagram downward connector

L12_PSORI_PUSTGEN

Control definitions

Control exclude L12_PAPULOSQUAMOUS

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 L40

Name in latin Psoriasis pustulosa generalisata

NAME	L12_PSORI_PUSTGEN
CONTROL_EXCLUDE	L12_PAPULOSQUAMOUS
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	L401
HD_ICD_9	6961B
HD_ICD_8	69610
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	L401
COD_ICD_9	6961B
COD_ICD_8	69610
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Show upset plot detailing case counts by codes

Or the full data table

Similar endpoints

↥

List of similar endpoints to Generalized pustular psoriasis based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

↥

Key figures

	All	Female	Male
Number of individuals	89	45	44
Unadjusted prevalence (%)	0.02	0.02	0.03
Mean age at first event (years)	52.25	49.81	54.75

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: L12_PSORI_PUSTGEN – Generalized pustular psoriasis
GWS hits:

Survival analyses between endpoints

↥

Not a core endpoint, no data to show.

Drugs most likely to be purchased after Generalized pustular psoriasis

↥

Endpoint not on priority list, no data to show.