Cicatricial pemphigoid

L12_PEMPHIGOID_CICA

mucous membrane pemphigoid: Mucous membrane pemphigoid is a bullous dermatosis characterised clinically by blistering of the mucous membranes followed by scarring, and immunologically by IgG, IgA and/or C3 deposits on the epidermal basement membrane.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 L12.1
Cause of death: ICD-10 L12.1

2 out of 7 registries used, show all original rules.

60

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Check minimum number of events None

60

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Include endpoints None

60

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Remove individuals based on genotype QC

60

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L12_PEMPHIGOID_CICA

Control definitions

Control exclude L12_BULLOUS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L12
Name in latin Pemphigoides cicatricalis

Summary Statistics

Key figures

All Female Male
Number of individuals 60 43 17
Unadjusted prevalence (%) 0.02 0.02 0.01
Mean age at first event (years) 60.31 59.49 62.39

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: L12_PEMPHIGOID_CICA – Cicatricial pemphigoid
GWS hits:

Survival analyses between endpoints

Plot

before Cicatricial pemphigoid
after Cicatricial pemphigoid

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Drugs most likely to be purchased after Cicatricial pemphigoid

Endpoint not on priority list, no data to show.