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Other acute skin changes due to ultraviolet radiation

DOID EFO MESH SNOMED PheWeb

L12_OTHACUSKINSUN

phototoxic dermatitis: a form of allergic contact dermatitis in which the allergen must be activated by light to sensitize the allergic response, and to cause a rash or other systemic effects on subsequent exposure. The second and subsequent exposures produce photoallergic skin conditions which are often eczematous. In rare cases the victims die.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 L56
Cause of death: ICD-10 L56

2 out of 7 registries used, show all original rules.

470

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Check minimum number of events None

470

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Include endpoints

1020

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Remove individuals based on genotype QC

996

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L12_OTHACUSKINSUN

Control definitions

Control exclude L12_RADIATIONRELATEDSKIN

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L55-L59
Name in latin Aliae commutationes acutae cutis e radiatione ultraviolacea

Similar endpoints

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List of similar endpoints to Other acute skin changes due to ultraviolet radiation based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 996 519 477
Unadjusted prevalence (%) 0.26 0.25 0.29
Mean age at first event (years) 42.16 42.52 41.77

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.23 [0.64, 2.40] 5.3e-1 154
15 years 0.01 0.91 [0.55, 1.52] 7.2e-1 70
5 years 0.00 1.52 [0.94, 2.47] 8.9e-2 34
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_OTHACUSKINSUN – Other acute skin changes due to ultraviolet radiation
GWS hits: 1

Survival analyses between endpoints

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Plot

before Other acute skin changes due to ultraviolet radiation
after Other acute skin changes due to ultraviolet radiation

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Drugs most likely to be purchased after Other acute skin changes due to ultraviolet radiation

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Endpoint not on priority list, no data to show.