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Lichen simplex chronicus and prurigo

DOID EFO MESH SNOMED PheWeb

L12_LICHSIMPANDPRURIGO

neurodermatitis: an itchy skin disease similar to atopic dermatitis. It tends to result in focal patches—one or many—that are due to frequent rubbing or scratching of the same area over time.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 L28
Cause of death: ICD-10 L28

2 out of 7 registries used, show all original rules.

1669

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Check minimum number of events None

1669

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Include endpoints

1755

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Remove individuals based on genotype QC

1703

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L12_LICHSIMPANDPRURIGO

Control definitions

Control exclude L12_DERMATITISECZEMA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L20-L30
Name in latin Neurodermatitis

Summary Statistics

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Key figures

All Female Male
Number of individuals 1703 971 732
Unadjusted prevalence (%) 0.45 0.46 0.44
Mean age at first event (years) 54.55 53.56 55.86

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.42 [0.68, 2.99] 3.5e-1 170
15 years 0.01 1.19 [0.63, 2.26] 5.9e-1 80
5 years 0.00 2.36 [1.37, 4.05] 1.8e-3 47
1 year 0.00 4.90 [2.65, 9.07] 4.2e-7 18

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_LICHSIMPANDPRURIGO – Lichen simplex chronicus and prurigo
GWS hits: 2

Survival analyses between endpoints

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Plot

before Lichen simplex chronicus and prurigo
after Lichen simplex chronicus and prurigo

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Lichen simplex chronicus and prurigo

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Endpoint not on priority list, no data to show.