Infections of the skin and subcutaneous tissue

DOID EFO MESH SNOMED PheWeb

L12_INFECT_SKIN

Tuberculosis, Cutaneous: Tuberculosis of the skin. It includes scrofuloderma and tuberculid, but not LUPUS VULGARIS.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 L00-L08

Cause of death: ICD-10 L00-L08

2 out of 7 registries used, show all original rules.

18895

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Check minimum number of events None

18895

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Include endpoints

L12_STAPHSCALDSKIN

L12_ABSCESS_CUT

L12_LYMPHADENITIS

L12_PILONIDALCYST

L12_INFECT_SKIN_OTHER

22084

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Remove individuals based on genotype QC

21308

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L12_INFECT_SKIN

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

NAME	L12_INFECT_SKIN
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	L12_STAPHSCALDSKIN\|L12_IMPETIGO\|L12_ABSCESS_CUT\|L12_CELLULITIS\|L12_LYMPHADENITIS\|L12_PILONIDALCYST\|L12_INFECT_SKIN_OTHER
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	L0
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	L0
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Or the full data table

Similar endpoints

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List of similar endpoints to Infections of the skin and subcutaneous tissue based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	21308	10378	10930
Unadjusted prevalence (%)	5.65	4.92	6.57
Mean age at first event (years)	45.13	43.46	46.71

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	3.65 [3.08, 4.32]	7.2e-51	2004
15 years	0.01	1.77 [1.51, 2.07]	1.5e-12	673
5 years	0.00	4.28 [3.69, 4.95]	4.4e-84	622
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_INFECT_SKIN – Infections of the skin and subcutaneous tissue
GWS hits: 2

Survival analyses between endpoints

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Plot

before Infections of the skin and subcutaneous tissue
after Infections of the skin and subcutaneous tissue

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Table

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Drugs most likely to be purchased after Infections of the skin and subcutaneous tissue

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Endpoint not on priority list, no data to show.