Granulomatous disorders of skin and subcutaneous tissue

DOID EFO MESH SNOMED PheWeb

L12_GRANULOMATOUSSKIN

Tuberculosis, Cutaneous: Tuberculosis of the skin. It includes scrofuloderma and tuberculid, but not LUPUS VULGARIS.

Endpoint definition

↥

FinnGen phenotype data

392423 individuals

diagram downward connector

Apply sex-specific rule None

392423

diagram downward connector

Check conditions None

392423

diagram downward connector

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 L92

Cause of death: ICD-10 L92

2 out of 7 registries used, show all original rules.

680

diagram downward connector

Check minimum number of events None

680

diagram downward connector

diagram downward connector

Include endpoints

L12_NECROLIPOIDIC

L12_FOREIGNBODYGRANULOMA

L12_GRANULOMASKINNAS

703

diagram downward connector

diagram downward connector

Remove individuals based on genotype QC

679

diagram downward connector

L12_GRANULOMATOUSSKIN

Control definitions

Control exclude L12_OTHERSKINSUBCUTIS

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 L80-L99

Name in latin Morbositates granulomatosae cutis et telae subcutaneae

NAME	L12_GRANULOMATOUSSKIN
CONTROL_EXCLUDE	L12_OTHERSKINSUBCUTIS
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	L12_GRANUANNU\|L12_NECROLIPOIDIC\|L12_GRANUFASC\|L12_FOREIGNBODYGRANULOMA\|L12_GRANULOMASKINNAS
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	L92
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	L92
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Show upset plot detailing case counts by codes

Or the full data table

Similar endpoints

↥

List of similar endpoints to Granulomatous disorders of skin and subcutaneous tissue based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

↥

Key figures

	All	Female	Male
Number of individuals	679	505	174
Unadjusted prevalence (%)	0.18	0.24	0.10
Mean age at first event (years)	47.65	45.23	54.66

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.07	4.85 [2.86, 8.22]	4.8e-9	53
15 years	0.02	2.83 [1.54, 5.21]	8.4e-4	26
5 years	0.00	2.98 [1.56, 5.67]	9.2e-4	10
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: L12_GRANULOMATOUSSKIN – Granulomatous disorders of skin and subcutaneous tissue
GWS hits: 1

Survival analyses between endpoints

↥

Plot

before Granulomatous disorders of skin and subcutaneous tissue
after Granulomatous disorders of skin and subcutaneous tissue

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Granulomatous disorders of skin and subcutaneous tissue

↥

Endpoint not on priority list, no data to show.