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Alopecia areata

DOID EFO MESH SNOMED PheWeb

L12_ALOPECAREATA

alopecia areata: Loss of scalp and body hair involving microscopically inflammatory patchy areas.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 L63
Hospital discharge: ICD-9 7040B|7040C
Hospital discharge: ICD-8 70400
Cause of death: ICD-10 L63
Cause of death: ICD-9 7040B|7040C
Cause of death: ICD-8 70400

2 out of 7 registries used, show all original rules.

718

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Check minimum number of events None

718

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Include endpoints None

718

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Remove individuals based on genotype QC

682

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L12_ALOPECAREATA

Control definitions

Control exclude L12_DISORDSKINAPPENDIX

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L60-L75
Name in latin Alopecia areata

Summary Statistics

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Key figures

All Female Male
Number of individuals 682 529 153
Unadjusted prevalence (%) 0.18 0.25 0.09
Mean age at first event (years) 42.12 42.33 41.39

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.36 [1.98, 5.69] 6.7e-6 18
15 years 0.02 2.67 [1.53, 4.65] 5.4e-4 12
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_ALOPECAREATA – Alopecia areata
GWS hits:

Survival analyses between endpoints

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Plot

before Alopecia areata
after Alopecia areata

loading spinner Loading survival analyses plot