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Allergic contact dermatitis

DOID EFO MESH SNOMED PheWeb

L12_ALLERGICCONTACT

allergic contact dermatitis: An inflammatory skin condition caused by an immune response to direct contact between the skin and an allergen. It consists of a delayed type of allergic reaction at the affected site with resulting red, swollen, and blistered skin that may itch or leak.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 L23
Hospital discharge: ICD-9 6920B|6921B|6922B|6924B|6924D|6924H|6924L|6925B|6925D|6926B|6926D
Cause of death: ICD-10 L23
Cause of death: ICD-9 6920B|6921B|6922B|6924B|6924D|6924H|6924L|6925B|6925D|6926B|6926D

2 out of 7 registries used, show all original rules.

4475

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Check minimum number of events None

4475

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Include endpoints None

4475

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Remove individuals based on genotype QC

4336

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L12_ALLERGICCONTACT

Control definitions

Control exclude L12_DERMATITISECZEMA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L20-L30
Name in latin Eczema (allergicum) ex contactu

Summary Statistics

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Key figures

All Female Male
Number of individuals 4336 3398 938
Unadjusted prevalence (%) 1.15 1.61 0.56
Mean age at first event (years) 47.12 46.04 51.05

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.39 [0.71, 2.71] 3.4e-1 181
15 years 0.01 1.23 [0.74, 2.06] 4.2e-1 97
5 years 0.00 1.72 [1.08, 2.73] 2.2e-2 40
1 year 0.00 2.67 [1.36, 5.21] 4.2e-3 11

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_ALLERGICCONTACT – Allergic contact dermatitis
GWS hits:

Survival analyses between endpoints

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Plot

before Allergic contact dermatitis
after Allergic contact dermatitis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Allergic contact dermatitis

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Endpoint not on priority list, no data to show.