Allergic contact dermatitis

L12_ALLERGICCONTACT

allergic contact dermatitis: An inflammatory skin condition caused by an immune response to direct contact between the skin and an allergen. It consists of a delayed type of allergic reaction at the affected site with resulting red, swollen, and blistered skin that may itch or leak.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 L23
Hospital discharge: ICD-9 6920B|6921B|6922B|6924B|6924D|6924H|6924L|6925B|6925D|6926B|6926D
Cause of death: ICD-10 L23
Cause of death: ICD-9 6920B|6921B|6922B|6924B|6924D|6924H|6924L|6925B|6925D|6926B|6926D

2 out of 7 registries used, show all original rules.

4475

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Check minimum number of events None

4475

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Include endpoints None

4475

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Remove individuals based on genotype QC

4336

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L12_ALLERGICCONTACT

Control definitions

Control exclude L12_DERMATITISECZEMA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L20-L30
Name in latin Eczema (allergicum) ex contactu

Summary Statistics

Key figures

All Female Male
Number of individuals 4336 3398 938
Unadjusted prevalence (%) 1.15 1.61 0.56
Mean age at first event (years) 47.12 46.04 51.05

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.39 [0.71, 2.71] 3.4e-1 181
15 years 0.01 1.23 [0.74, 2.06] 4.2e-1 97
5 years 0.00 1.72 [1.08, 2.73] 2.2e-2 40
1 year 0.00 2.67 [1.36, 5.21] 4.2e-3 11

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: L12_ALLERGICCONTACT – Allergic contact dermatitis
GWS hits:

Survival analyses between endpoints

Plot

before Allergic contact dermatitis
after Allergic contact dermatitis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Allergic contact dermatitis

Endpoint not on priority list, no data to show.