Other acantholytic disorders

DOID EFO MESH SNOMED PheWeb

L12_ACANTHOLYTIC

liver disease: A disease involving the liver.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 L11

Cause of death: ICD-10 L11

2 out of 7 registries used, show all original rules.

62

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Check minimum number of events None

62

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Include endpoints

L12_GROVER

62

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Remove individuals based on genotype QC

61

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L12_ACANTHOLYTIC

Control definitions

Control exclude L12_BULLOUS

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 L10-L14

Name in latin Aliae morbositates acantholyticae

NAME	L12_ACANTHOLYTIC
CONTROL_EXCLUDE	L12_BULLOUS
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	L12_KERATFOLL\|L12_GROVER\|L12_ACANTHNAS
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	L11
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	L11
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Similar endpoints

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List of similar endpoints to Other acantholytic disorders based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	61	19	42
Unadjusted prevalence (%)	0.02	0.01	0.03
Mean age at first event (years)	66.30	60.58	68.89

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_ACANTHOLYTIC – Other acantholytic disorders
GWS hits:

Survival analyses between endpoints

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Plot

before Other acantholytic disorders
after Other acantholytic disorders

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Table

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Drugs most likely to be purchased after Other acantholytic disorders

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Endpoint not on priority list, no data to show.