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Acanthosis nigricans

DOID EFO MESH SNOMED PheWeb

L12_ACANTHNIGRICANS

acanthosis nigricans: a brown to black, poorly defined, velvety hyperpigmentation of the skin. It is usually found in body folds, such as the posterior and lateral folds of the neck, the armpits, groin, navel, forehead, and other areas.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 L83
Hospital discharge: ICD-9 7012A
Hospital discharge: ICD-8 7011
Cause of death: ICD-10 L83
Cause of death: ICD-9 7012A
Cause of death: ICD-8 7011

2 out of 7 registries used, show all original rules.

100

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Check minimum number of events None

100

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Include endpoints None

100

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Remove individuals based on genotype QC

93

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L12_ACANTHNIGRICANS

Control definitions

Control exclude L12_OTHERSKINSUBCUTIS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 L80-L99
Name in latin Acanthosis nigricans

Summary Statistics

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Key figures

All Female Male
Number of individuals 93 56 37
Unadjusted prevalence (%) 0.02 0.03 0.02
Mean age at first event (years) 34.89 36.50 32.44

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: L12_ACANTHNIGRICANS – Acanthosis nigricans
GWS hits: 1

Survival analyses between endpoints

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Plot

before Acanthosis nigricans
after Acanthosis nigricans

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Acanthosis nigricans

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Endpoint not on priority list, no data to show.