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Other diseases of pancreas

DOID EFO MESH SNOMED PheWeb

K11_PANCOTH

pancreas disease: A non-neoplastic or neoplastic disorder that affects the pancreas. Representative examples of non-neoplastic disorders include pancreatitis and pancreatic insufficiency. Representative examples of neoplastic disorders include cystadenomas, carcinomas, lymphomas, and neuroendocrine neoplasms. [ NCIT:C26842 ]

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K86.2, K86.3, K86.8, K86.9
Hospital discharge: ICD-9 577[2-9]
Hospital discharge: ICD-8 5779
Cause of death: ICD-10 K86.2, K86.3, K86.8, K86.9
Cause of death: ICD-9 577[2-9]
Cause of death: ICD-8 5779

2 out of 7 registries used, show all original rules.

1829

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Check minimum number of events None

1829

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Include endpoints None

1829

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Remove individuals based on genotype QC

1791

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K11_PANCOTH

Control definitions

Control exclude K11_GALLBILPANC

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 1791 774 1017
Unadjusted prevalence (%) 0.47 0.37 0.61
Mean age at first event (years) 59.13 59.88 58.55

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.00 [1.52, 5.93] 1.6e-3 274
15 years 0.01 1.71 [0.92, 3.18] 9.2e-2 104
5 years 0.01 4.77 [3.04, 7.48] 1.0e-11 86
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_PANCOTH – Other diseases of pancreas
GWS hits: 3

Survival analyses between endpoints

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Plot

before Other diseases of pancreas
after Other diseases of pancreas

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Other diseases of pancreas

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Endpoint not on priority list, no data to show.