Other diseases of the digestive system

DOID EFO MESH PheWeb

K11_OTHDIG

dumping syndrome: Gastrointestinal symptoms resulting from an absent or nonfunctioning pylorus.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K90-K93

Cause of death: ICD-10 K90-K93

2 out of 7 registries used, show all original rules.

15875

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Check minimum number of events None

15875

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Include endpoints

K11_COELIAC

K11_DISDIGINOTH

16752

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Remove individuals based on genotype QC

16222

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K11_OTHDIG

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

NAME	K11_OTHDIG
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	K11_COELIAC\|K11_MALABSORB\|K11_POSTOPDIS\|K11_GIBLEEDING\|K11_OTHDISDIG\|K11_DISDIGINOTH
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	K9
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	K9
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Or the full data table

Similar endpoints

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List of similar endpoints to Other diseases of the digestive system based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	16222	7623	8599
Unadjusted prevalence (%)	4.30	3.62	5.17
Mean age at first event (years)	57.29	52.74	61.32

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.06	4.18 [3.46, 5.05]	1.6e-49	3473
15 years	0.01	1.69 [1.44, 1.97]	5.5e-11	1032
5 years	0.01	4.55 [4.05, 5.11]	<1e-100	1127
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_OTHDIG – Other diseases of the digestive system
GWS hits: 8

Survival analyses between endpoints

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Plot

before Other diseases of the digestive system
after Other diseases of the digestive system

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Table

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Drugs most likely to be purchased after Other diseases of the digestive system

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Endpoint not on priority list, no data to show.