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Dentofacial anomalies [including malocclusion]

PheWeb

K11_DENTOFACIAL_ANOMALIES

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K07
Cause of death: ICD-10 K07

2 out of 7 registries used, show all original rules.

10238

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Check minimum number of events None

10238

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Include endpoints None

10238

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Remove individuals based on genotype QC

9866

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K11_DENTOFACIAL_ANOMALIES

Control definitions

Control exclude K11_ORAL

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF5

Similar endpoints

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List of similar endpoints to Dentofacial anomalies [including malocclusion] based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All Female Male
Number of individuals 9866 7097 2769
Unadjusted prevalence (%) 2.62 3.37 1.67
Mean age at first event (years) 43.48 42.98 44.76

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.82 [1.22, 2.70] 3.2e-3 232
15 years 0.01 1.14 [0.76, 1.70] 5.3e-1 104
5 years 0.00 2.32 [1.60, 3.36] 8.0e-6 66
1 year 0.00 3.79 [2.24, 6.39] 6.0e-7 20

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_DENTOFACIAL_ANOMALIES – Dentofacial anomalies [including malocclusion]
GWS hits:

Survival analyses between endpoints

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Plot

before Dentofacial anomalies [including malocclusion]
after Dentofacial anomalies [including malocclusion]

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Dentofacial anomalies [including malocclusion]

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Endpoint not on priority list, no data to show.