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Cholelithiasis

DOID EFO MESH SNOMED PheWeb

K11_CHOLELITH

cholelithiasis: The presence of calculi in the gallbladder.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K80
Hospital discharge: ICD-9 574
Hospital discharge: ICD-8 574
Cause of death: ICD-10 K80
Cause of death: ICD-9 574
Cause of death: ICD-8 574

2 out of 7 registries used, show all original rules.

38311

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Check minimum number of events None

38311

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Include endpoints None

38311

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Remove individuals based on genotype QC

37041

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K11_CHOLELITH

Control definitions

Control exclude K11_GALLBILPANC

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 K80-K87
Name in latin Cholelithiasis

Summary Statistics

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Key figures

All Female Male
Number of individuals 37041 24990 12051
Unadjusted prevalence (%) 9.82 11.85 7.25
Mean age at first event (years) 52.21 48.77 59.35

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.59 [1.42, 1.78] 4.4e-16 5048
15 years 0.01 1.06 [0.97, 1.16] 1.9e-1 2182
5 years 0.00 1.63 [1.48, 1.78] 2.3e-25 1056
1 year 0.00 4.40 [3.88, 4.99] <1e-100 536

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_CHOLELITH – Cholelithiasis
GWS hits: 75

Survival analyses between endpoints

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Plot

before Cholelithiasis
after Cholelithiasis

loading spinner Loading survival analyses plot