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Acute pancreatitis

DOID EFO MESH SNOMED PheWeb

K11_ACUTPANC

acute pancreatitis: An acute inflammatory process that leads to necrosis of the pancreatic parenchyma. Signs and symptoms include severe abdominal pain, nausea, vomiting, diarrhea, fever, and shock. Causes include alcohol consumption, presence of gallstones, trauma, and drugs.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 K85
Hospital discharge: ICD-9 5770
Hospital discharge: ICD-8 5770
Cause of death: ICD-10 K85
Cause of death: ICD-9 5770
Cause of death: ICD-8 5770

2 out of 7 registries used, show all original rules.

6399

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Check minimum number of events None

6399

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Include endpoints None

6399

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Remove individuals based on genotype QC

6223

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K11_ACUTPANC

Control definitions

Control exclude K11_GALLBILPANC

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 K80-K87
Name in latin Pancreatitis acuta

Summary Statistics

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Key figures

All Female Male
Number of individuals 6223 2430 3793
Unadjusted prevalence (%) 1.65 1.15 2.28
Mean age at first event (years) 53.65 52.25 54.55

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 3.71 [3.02, 4.55] 4.1e-36 1169
15 years 0.01 1.99 [1.69, 2.34] 2.2e-16 446
5 years 0.00 3.44 [2.91, 4.07] 2.5e-47 273
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_ACUTPANC – Acute pancreatitis
GWS hits: 6

Survival analyses between endpoints

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Plot

before Acute pancreatitis
after Acute pancreatitis

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Acute pancreatitis

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Endpoint not on priority list, no data to show.