Acute upper respiratory infections


sinusitis: An acute or chronic inflammatory process affecting the mucous membranes of any sinus cavity.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None


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Check conditions None


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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 J00-J06
Cause of death: ICD-10 J00-J06

2 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Remove individuals based on genotype QC


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Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Acute upper respiratory infections based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 69111 34088 35023
Unadjusted prevalence (%) 18.33 16.17 21.06
Mean age at first event (years) 32.98 36.07 29.96


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.23 [1.96, 2.54] 1.4e-34 4325
15 years 0.01 1.26 [1.12, 1.41] 6.0e-5 1510
5 years 0.00 2.83 [2.56, 3.13] 9.1e-92 1235
1 year 0.00 7.78 [6.86, 8.83] <1e-100 712

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: J10_UPPERINFEC – Acute upper respiratory infections
GWS hits: 7

Survival analyses between endpoints


before Acute upper respiratory infections
after Acute upper respiratory infections

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Drugs most likely to be purchased after Acute upper respiratory infections

Endpoint not on priority list, no data to show.