Other diseases of pleura

J10_PLEURA

respiratory system disease: A non-neoplastic or neoplastic disorder that affects the respiratory system. Representative examples include pneumonia, chronic obstructive pulmonary disease, pulmonary failure, lung adenoma, lung carcinoma, and tracheal carcinoma.

Endpoint definition

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FinnGen phenotype data

392423 individuals

Apply sex-specific rule None

392423

Check conditions None

392423

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 J90-J94, J95-J99

Cause of death: ICD-10 J90-J94, J95-J99

2 out of 7 registries used, show all original rules.

14892

Check minimum number of events None

14892

Include endpoints

J10_PLEUREFFUSION

J10_PLEURPLAGUE

J10_PNEUMOTHORAX

J10_PLEUROTH

15918

Remove individuals based on genotype QC

15441

J10_PLEURA

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

NAME	J10_PLEURA
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	J10_PLEUREFFUSION\|J10_PLEURPLAGUE\|J10_PNEUMOTHORAX\|J10_PLEUROTH
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	J9[0-9]
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	J9[0-9]
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Show upset plot detailing case counts by codes

Or the full data table

Similar endpoints

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List of similar endpoints to Other diseases of pleura based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	15441	4862	10579
Unadjusted prevalence (%)	4.09	2.31	6.36
Mean age at first event (years)	64.14	61.19	65.50

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.08	5.73 [4.89, 6.70]	<1e-100	5246
15 years	0.01	1.95 [1.70, 2.23]	5.4e-22	1275
5 years	0.01	5.84 [5.29, 6.45]	<1e-100	1614
1 year	0.01	29.29 [26.32, 32.60]	<1e-100	2085

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: J10_PLEURA – Other diseases of pleura
GWS hits: 2

Survival analyses between endpoints

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Plot

before Other diseases of pleura
after Other diseases of pleura

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Other diseases of pleura

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Endpoint not on priority list, no data to show.

≡ Risteys

R9

R8

R7

R6

R5

R4

R3