All influenza

J10_INFLUENZA

influenza: An acute viral infection of the respiratory tract, occurring in isolated cases, in epidemics, or in pandemics; it is caused by serologically different strains of viruses (influenzaviruses) designated A, B, and C, has a 3-day incubation period, and usually lasts for 3 to 10 days. It is marked by inflammation of the nasal mucosa, pharynx, and conjunctiva; headache; myalgia; often fever, chills, and prostration; and occasionally involvement of the myocardium or central nervous system.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 J09, J10, J11
Hospital discharge: ICD-9 487
Hospital discharge: ICD-8 47[0-4]
Cause of death: ICD-10 J09, J10, J11
Cause of death: ICD-9 487
Cause of death: ICD-8 47[0-4]

2 out of 7 registries used, show all original rules.

8891

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Check minimum number of events None

8891

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Include endpoints None

8891

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Remove individuals based on genotype QC

8555

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J10_INFLUENZA

Control definitions

Control exclude J10_INFLUPNEU

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 8555 3868 4687
Unadjusted prevalence (%) 2.27 1.83 2.82
Mean age at first event (years) 51.60 53.52 50.01

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 4.58 [3.54, 5.91] 3.5e-31 1088
15 years 0.01 1.08 [0.87, 1.34] 5.1e-1 196
5 years 0.00 4.20 [3.34, 5.28] 1.2e-34 440
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: J10_INFLUENZA – All influenza
GWS hits:

Survival analyses between endpoints

Plot

before All influenza
after All influenza

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Drugs most likely to be purchased after All influenza

Endpoint not on priority list, no data to show.