Emphysema

DOID EFO MESH SNOMED PheWeb

J10_EMPHYSEMA

pleural empyema: The presence of pus in the thoracic cavity, between the visceral and parietal pleura. [database_cross_reference: NCIT:P378]

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 J43

Hospital discharge: ICD-9 492

Hospital discharge: ICD-8 492

Cause of death: ICD-10 J43

Cause of death: ICD-9 492

Cause of death: ICD-8 492

2 out of 7 registries used, show all original rules.

1936

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Check minimum number of events None

1936

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Include endpoints None

1936

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Remove individuals based on genotype QC

1885

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J10_EMPHYSEMA

Control definitions

Control exclude J10_LOWCHRON

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 J40-J47

Name in latin Emphysema pulmonale

NAME	J10_EMPHYSEMA
CONTROL_EXCLUDE	J10_LOWCHRON
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	J43
HD_ICD_9	492
HD_ICD_8	492
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	J43
COD_ICD_9	492
COD_ICD_8	492
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Or the full data table

Similar endpoints

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List of similar endpoints to Emphysema based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1885	473	1412
Unadjusted prevalence (%)	0.50	0.22	0.85
Mean age at first event (years)	66.70	62.24	68.19

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: J10_EMPHYSEMA – Emphysema
GWS hits: 2

Survival analyses between endpoints

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Plot

before Emphysema
after Emphysema

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Emphysema

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Endpoint not on priority list, no data to show.