Pneumoconiosis due to asbestos and other mineral fibres

DOID EFO MESH SNOMED PheWeb

J10_ASBESTPNEUMOC

asbestosis: A pneumoconiosis caused by inhalation and retention of asbestos fibers.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 J61

Hospital discharge: ICD-9 501

Hospital discharge: ICD-8 5152

Cause of death: ICD-10 J61

Cause of death: ICD-9 501

Cause of death: ICD-8 5152

2 out of 7 registries used, show all original rules.

625

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Check minimum number of events None

625

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Include endpoints None

625

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Remove individuals based on genotype QC

610

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J10_ASBESTPNEUMOC

Control definitions

Control exclude J10_EXTERLUNG

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 J60-J70

Name in latin Asbestosis

NAME	J10_ASBESTPNEUMOC
CONTROL_EXCLUDE	J10_EXTERLUNG
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	J61
HD_ICD_9	501
HD_ICD_8	5152
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	J61
COD_ICD_9	501
COD_ICD_8	5152
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Similar endpoints

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List of similar endpoints to Pneumoconiosis due to asbestos and other mineral fibres based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

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Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	610	22	588
Unadjusted prevalence (%)	0.16	0.01	0.35
Mean age at first event (years)	69.46	60.88	69.78

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: J10_ASBESTPNEUMOC – Pneumoconiosis due to asbestos and other mineral fibres
GWS hits: 1

Survival analyses between endpoints

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Plot

before Pneumoconiosis due to asbestos and other mineral fibres
after Pneumoconiosis due to asbestos and other mineral fibres

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Table

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Drugs most likely to be purchased after Pneumoconiosis due to asbestos and other mineral fibres

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Endpoint not on priority list, no data to show.