Increased muscle tone

INCREASEDMUSCLETONE

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 R29.0, R29.3

Hospital discharge: ICD-9 7817

Hospital discharge: ICD-8 78850

Cause of death: ICD-10 R29.0, R29.3

Cause of death: ICD-9 7817

Cause of death: ICD-8 78850

2 out of 7 registries used, show all original rules.

79

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Check minimum number of events None

79

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Include endpoints

177

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Remove individuals based on genotype QC

173

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INCREASEDMUSCLETONE

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF3

NAME	INCREASEDMUSCLETONE
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	M13_MUSCONTRAC
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	R29[0\|3]
HD_ICD_9	7817
HD_ICD_8	78850
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	R29[0\|3]
COD_ICD_9	7817
COD_ICD_8	78850
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Show upset plot detailing case counts by codes

Or the full data table

Similar endpoints

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List of similar endpoints to Increased muscle tone based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Contracture of muscle

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	173	106	67
Unadjusted prevalence (%)	0.05	0.05	0.04
Mean age at first event (years)	46.38	42.86	51.94

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: INCREASEDMUSCLETONE – Increased muscle tone
GWS hits: 1

Survival analyses between endpoints

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Not a core endpoint, no data to show.

Drugs most likely to be purchased after Increased muscle tone

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Endpoint not on priority list, no data to show.