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Progressive vascular leukoencephalopathy

DOID EFO MESH PheWeb

I9_PROGVASC

brain aneurysm: A congenital or acquired aneurysm within the cranium.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 I67.3
Cause of death: ICD-10 I67.3

2 out of 7 registries used, show all original rules.

696

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Check minimum number of events None

696

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Include endpoints None

696

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Remove individuals based on genotype QC

673

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I9_PROGVASC

Control definitions

Control exclude I9_CEREBVASC

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I67
Name in latin Leucoencephalopathia vascularis progressiva

Summary Statistics

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Key figures

All Female Male
Number of individuals 673 337 336
Unadjusted prevalence (%) 0.18 0.16 0.20
Mean age at first event (years) 76.96 76.79 77.12

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.11 7.46 [3.36, 16.60] 8.2e-7 155
15 years 0.01 2.00 [0.87, 4.58] 1.0e-1 41
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_PROGVASC – Progressive vascular leukoencephalopathy
GWS hits:

Survival analyses between endpoints

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Plot

before Progressive vascular leukoencephalopathy
after Progressive vascular leukoencephalopathy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Progressive vascular leukoencephalopathy

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Endpoint not on priority list, no data to show.