Progressive vascular leukoencephalopathy

I9_PROGVASC

brain aneurysm: A congenital or acquired aneurysm within the cranium.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 I67.3
Cause of death: ICD-10 I67.3

2 out of 7 registries used, show all original rules.

696

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Check minimum number of events None

696

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Include endpoints None

696

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Remove individuals based on genotype QC

673

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I9_PROGVASC

Control definitions

Control exclude I9_CEREBVASC

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I67
Name in latin Leucoencephalopathia vascularis progressiva

Summary Statistics

Key figures

All Female Male
Number of individuals 673 337 336
Unadjusted prevalence (%) 0.18 0.16 0.20
Mean age at first event (years) 76.96 76.79 77.12

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.11 7.46 [3.36, 16.60] 8.2e-7 155
15 years 0.01 2.00 [0.87, 4.58] 1.0e-1 41
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_PROGVASC – Progressive vascular leukoencephalopathy
GWS hits:

Survival analyses between endpoints

Plot

before Progressive vascular leukoencephalopathy
after Progressive vascular leukoencephalopathy

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Progressive vascular leukoencephalopathy

Endpoint not on priority list, no data to show.