Other diseases of pericardium

I9_PERICAOTH

Cardiac Tamponade: Compression of the heart by accumulated fluid (PERICARDIAL EFFUSION) or blood (HEMOPERICARDIUM) in the PERICARDIUM surrounding the heart. The affected cardiac functions and CARDIAC OUTPUT can range from minimal to total hemodynamic collapse.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 I31
Hospital discharge: ICD-9 423
Hospital discharge: ICD-8 423
Cause of death: ICD-10 I31
Cause of death: ICD-9 423
Cause of death: ICD-8 423

2 out of 7 registries used, show all original rules.

1173

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Check minimum number of events None

1173

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Include endpoints None

1173

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Remove individuals based on genotype QC

1135

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I9_PERICAOTH

Control definitions

Control exclude I9_OTHHEART

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I30-I52
Name in latin Alii morbi pericardii

Summary Statistics

Key figures

All Female Male
Number of individuals 1135 473 662
Unadjusted prevalence (%) 0.30 0.22 0.40
Mean age at first event (years) 61.02 59.66 61.99

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.13 9.42 [6.19, 14.33] 1.3e-25 216
15 years 0.02 2.80 [1.83, 4.29] 2.1e-6 57
5 years 0.01 5.10 [3.03, 8.59] 9.4e-10 58
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_PERICAOTH – Other diseases of pericardium
GWS hits:

Survival analyses between endpoints

Plot

before Other diseases of pericardium
after Other diseases of pericardium

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Drugs most likely to be purchased after Other diseases of pericardium

Endpoint not on priority list, no data to show.