Other other unspecified disorders of the circulatory system

I9_OTHOTH

cardiovascular disease: A disease involving the cardiovascular system.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 I97, I98*, I99
Hospital discharge: ICD-9 4590A|459[8-9]
Hospital discharge: ICD-8 4581|4589
Cause of death: ICD-10 I97, I98*, I99
Cause of death: ICD-9 4590A|459[8-9]
Cause of death: ICD-8 4581|4589

2 out of 7 registries used, show all original rules.

1018

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Check minimum number of events None

1018

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Include endpoints None

1018

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Remove individuals based on genotype QC

1002

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I9_OTHOTH

Control definitions

Control exclude I9_OTH

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 1002 532 470
Unadjusted prevalence (%) 0.27 0.25 0.28
Mean age at first event (years) 58.03 56.86 59.35

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.28 [0.97, 5.36] 5.9e-2 183
15 years 0.01 1.50 [0.81, 2.79] 2.0e-1 74
5 years 0.00 3.02 [1.89, 4.83] 4.1e-6 45
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_OTHOTH – Other other unspecified disorders of the circulatory system
GWS hits:

Survival analyses between endpoints

Plot

before Other other unspecified disorders of the circulatory system
after Other other unspecified disorders of the circulatory system

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Drugs most likely to be purchased after Other other unspecified disorders of the circulatory system

Endpoint not on priority list, no data to show.