Other specified cerebrovascular diseases, other cerebrovascular disorders in diseases classified elsewhere

I9_CEREBDOTH

cerebrovascular disorder: A disorder resulting from inadequate blood flow in the vessels that supply the brain. Representative examples include cerebrovascular ischemia, cerebral embolism, and cerebral infarction.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital discharge: ICD-9 436|4371|4378X
Hospital discharge: ICD-8 438
Cause of death: ICD-9 436|4371|4378X
Cause of death: ICD-8 438

2 out of 7 registries used, show all original rules.

2016

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Check minimum number of events None

2016

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Include endpoints None

2016

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Remove individuals based on genotype QC

1949

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I9_CEREBDOTH

Control definitions

Control exclude I9_CEREBVASC

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 1949 839 1110
Unadjusted prevalence (%) 0.52 0.40 0.67
Mean age at first event (years) 65.30 64.01 66.27

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 4.08 [3.03, 5.51] 3.0e-20 606
15 years 0.01 1.77 [1.31, 2.40] 2.4e-4 222
5 years 0.00 3.68 [2.89, 4.69] 4.5e-26 198
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_CEREBDOTH – Other specified cerebrovascular diseases, other cerebrovascular disorders in diseases classified elsewhere
GWS hits: 1

Survival analyses between endpoints

Plot

before Other specified cerebrovascular diseases, other cerebrovascular disorders in diseases classified elsewhere
after Other specified cerebrovascular diseases, other cerebrovascular disorders in diseases classified elsewhere

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Drugs most likely to be purchased after Other specified cerebrovascular diseases, other cerebrovascular disorders in diseases classified elsewhere

Endpoint not on priority list, no data to show.