Vestibular neuronitis

H8_VESTIBNEUR

vestibular neuronitis: Idiopathic inflammation of the vestibular nerve, characterized clinically by the acute or subacute onset of vertigo; nausea; and imbalance. The cochlear nerve is typically spared and hearing loss and tinnitus do not usually occur. Symptoms usually resolve over a period of days to weeks. (Adams et al., Principles of Neurology, 6th ed, p304)

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H81.2
Hospital discharge: ICD-9 3861
Cause of death: ICD-10 H81.2
Cause of death: ICD-9 3861

2 out of 7 registries used, show all original rules.

2452

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Check minimum number of events None

2452

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Include endpoints None

2452

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Remove individuals based on genotype QC

2379

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H8_VESTIBNEUR

Control definitions

Control exclude H8_INNER

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H81
Name in latin Neuronitis vestibularis

Summary Statistics

Key figures

All Female Male
Number of individuals 2379 1336 1043
Unadjusted prevalence (%) 0.63 0.63 0.63
Mean age at first event (years) 54.57 53.13 56.40

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.07 [0.62, 1.85] 8.0e-1 149
15 years 0.01 0.81 [0.52, 1.26] 3.5e-1 69
5 years 0.00 1.47 [0.93, 2.35] 1.0e-1 34
1 year 0.00 2.48 [1.24, 4.94] 1.0e-2 10

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H8_VESTIBNEUR – Vestibular neuronitis
GWS hits: 1

Survival analyses between endpoints

Plot

before Vestibular neuronitis
after Vestibular neuronitis

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Drugs most likely to be purchased after Vestibular neuronitis

Endpoint not on priority list, no data to show.