Presbycusis

H8_HL_PRESBY

No definition available.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H91.1
Hospital discharge: ICD-9 3880
Hospital discharge: excluded ICD-9 2880X
Cause of death: ICD-10 H91.1
Cause of death: ICD-9 3880
Cause of death: excluded ICD-9 2880X

2 out of 7 registries used, show all original rules.

4274

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Check minimum number of events None

4274

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Include endpoints None

4274

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Remove individuals based on genotype QC

4140

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H8_HL_PRESBY

Control definitions

Control exclude H8_OTHEREAR

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H91
Name in latin Presbyacusis

Summary Statistics

Key figures

All Female Male
Number of individuals 4140 1844 2296
Unadjusted prevalence (%) 1.10 0.87 1.38
Mean age at first event (years) 75.82 75.73 75.89

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.23 [1.74, 2.87] 2.8e-10 1060
15 years 0.01 1.18 [0.95, 1.46] 1.4e-1 504
5 years 0.00 1.93 [1.61, 2.30] 5.9e-13 378
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H8_HL_PRESBY – Presbycusis
GWS hits: 1

Survival analyses between endpoints

Plot

before Presbycusis
after Presbycusis

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Drugs most likely to be purchased after Presbycusis

Endpoint not on priority list, no data to show.