Sudden idiopathic hearing loss

H8_HL_IDIOP

sensorineural hearing loss: Hearing loss in which the root cause lies in the inner ear or sensory organ (cochlea and associated structures) or the vestibulocochlear nerve (cranial nerve VIII).

Endpoint definition

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FinnGen phenotype data

392423 individuals

Apply sex-specific rule None

392423

Check conditions None

392423

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H91.2

Hospital discharge: ICD-9 3882

Cause of death: ICD-10 H91.2

Cause of death: ICD-9 3882

2 out of 7 registries used, show all original rules.

2945

Check minimum number of events None

2945

Include endpoints None

2945

Remove individuals based on genotype QC

2848

H8_HL_IDIOP

Control definitions

Control exclude H8_OTHEREAR

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Parent code in ICD-10 H91

Name in latin Hypacusis acuta idiopathica

NAME	H8_HL_IDIOP
CONTROL_EXCLUDE	H8_OTHEREAR
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	H912
HD_ICD_9	3882
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	H912
COD_ICD_9	3882
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Or the full data table

Similar endpoints

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List of similar endpoints to Sudden idiopathic hearing loss based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	2848	1479	1369
Unadjusted prevalence (%)	0.76	0.70	0.82
Mean age at first event (years)	57.11	55.24	59.13

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.25 [0.82, 1.91]	2.9e-1	229
15 years	0.01	0.86 [0.61, 1.21]	3.8e-1	108
5 years	0.00	1.53 [1.06, 2.19]	2.2e-2	62
1 year	0.00	1.78 [0.99, 3.21]	5.6e-2	14

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H8_HL_IDIOP – Sudden idiopathic hearing loss
GWS hits:

Survival analyses between endpoints

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Plot

before Sudden idiopathic hearing loss
after Sudden idiopathic hearing loss

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Table

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Drugs most likely to be purchased after Sudden idiopathic hearing loss

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≡ Risteys

R9

R8

R7

R6

R5

R4

R3

Sudden idiopathic hearing loss

Endpoint definition

All original rules

Upset plot

Case counts by code for Sudden idiopathic hearing loss (H8_HL_IDIOP)

Similar endpoints

Summary Statistics

Key figures

Mortality

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Authentication required

Survival analyses between endpoints

Plot

Table

Drugs most likely to be purchased after Sudden idiopathic hearing loss