Sudden idiopathic hearing loss

H8_HL_IDIOP

sensorineural hearing loss: Hearing loss in which the root cause lies in the inner ear or sensory organ (cochlea and associated structures) or the vestibulocochlear nerve (cranial nerve VIII).

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H91.2
Hospital discharge: ICD-9 3882
Cause of death: ICD-10 H91.2
Cause of death: ICD-9 3882

2 out of 7 registries used, show all original rules.

2945

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Check minimum number of events None

2945

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Include endpoints None

2945

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Remove individuals based on genotype QC

2848

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H8_HL_IDIOP

Control definitions

Control exclude H8_OTHEREAR

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H91
Name in latin Hypacusis acuta idiopathica

Summary Statistics

Key figures

All Female Male
Number of individuals 2848 1479 1369
Unadjusted prevalence (%) 0.76 0.70 0.82
Mean age at first event (years) 57.11 55.24 59.13

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.25 [0.82, 1.91] 2.9e-1 229
15 years 0.01 0.86 [0.61, 1.21] 3.8e-1 108
5 years 0.00 1.53 [1.06, 2.19] 2.2e-2 62
1 year 0.00 1.78 [0.99, 3.21] 5.6e-2 14

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H8_HL_IDIOP – Sudden idiopathic hearing loss
GWS hits:

Survival analyses between endpoints

Plot

before Sudden idiopathic hearing loss
after Sudden idiopathic hearing loss

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Sudden idiopathic hearing loss