Diseases of external ear

H8_EXTERNAL

otitis externa: Inflammation of the anatomical structures of the outer ear and ear canal secondary to an infectious process. Bacterial etiology is most common, but fungal infection is also possible. Symptoms include erythema, edema, and pain.

Endpoint definition

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FinnGen phenotype data

392423 individuals

Apply sex-specific rule None

392423

Check conditions None

392423

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H60-H62

Cause of death: ICD-10 H60-H62

2 out of 7 registries used, show all original rules.

9994

Check minimum number of events None

9994

Include endpoints

H8_EXTOTITIS

H8_PERCHRONDR

H8_PINNADIS

H8_CERUMEN

H8_STENOEXTCAN

H8_EXTDISNAS

H8_EXTDISINOTH

10677

Remove individuals based on genotype QC

10272

H8_EXTERNAL

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

NAME	H8_EXTERNAL
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	H8_EXTOTITIS\|H8_PERCHRONDR\|H8_PINNADIS\|H8_CERUMEN\|H8_STENOEXTCAN\|H8_EXTDISNAS\|H8_EXTDISINOTH
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	H6[0-2]
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	H6[0-2]
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Or the full data table

Similar endpoints

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List of similar endpoints to Diseases of external ear based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	10272	5309	4963
Unadjusted prevalence (%)	2.72	2.52	2.98
Mean age at first event (years)	53.39	50.45	56.54

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.65 [1.21, 2.24]	1.6e-3	765
15 years	0.01	1.01 [0.77, 1.34]	9.2e-1	340
5 years	0.00	1.99 [1.59, 2.50]	2.4e-9	240
1 year	0.00	2.95 [2.20, 3.95]	5.3e-13	73

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H8_EXTERNAL – Diseases of external ear
GWS hits: 1

Survival analyses between endpoints

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Plot

before Diseases of external ear
after Diseases of external ear

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Table

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Drugs most likely to be purchased after Diseases of external ear

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Endpoint not on priority list, no data to show.

≡ Risteys

R9

R8

R7

R6

R5

R4

R3