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Pterygium

DOID EFO MESH SNOMED PheWeb

H7_PTERYGIUM

pterygium: A wedge-shaped fibrovascular lesion arising from the bulbar conjunctiva and extending to the cornea. It is caused by chronic exposure to solar ultraviolet radiation, heat, and dust. It may cause severe vision loss. Studies have linked pterygium to neoplastic proliferation and suggest that it may be a stem cell disorder.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H11.0
Hospital discharge: ICD-9 3724
Hospital discharge: ICD-8 372
Cause of death: ICD-10 H11.0
Cause of death: ICD-9 3724
Cause of death: ICD-8 372

2 out of 7 registries used, show all original rules.

776

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Check minimum number of events None

776

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Include endpoints None

776

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Remove individuals based on genotype QC

718

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H7_PTERYGIUM

Control definitions

Control exclude H7_CONJUNCTIVA

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H11
Name in latin Pterygium

Summary Statistics

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Key figures

All Female Male
Number of individuals 718 254 464
Unadjusted prevalence (%) 0.19 0.12 0.28
Mean age at first event (years) 59.39 56.20 61.14

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.16 [0.55, 2.48] 7.0e-1 98
15 years 0.01 1.03 [0.59, 1.80] 9.3e-1 53
5 years 0.00 0.66 [0.32, 1.37] 2.7e-1 10
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_PTERYGIUM – Pterygium
GWS hits:

Survival analyses between endpoints

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Plot

before Pterygium
after Pterygium

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Pterygium

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Endpoint not on priority list, no data to show.