Other disorders of optic [2nd] nerve and visual pathways

DOID MESH PheWeb

H7_OPTNEUROTH

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H47

Cause of death: ICD-10 H47

2 out of 7 registries used, show all original rules.

1603

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Check minimum number of events None

1603

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Include endpoints

H7_PAPILLOEDEMA

H7_OPTICDISCOTH

H7_VISUALPATHOTH

H7_VISUALCORTEXOTH

H7_VISUALPATHNAS

1694

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Remove individuals based on genotype QC

1631

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H7_OPTNEUROTH

Control definitions

Control exclude H7_OPTNERVE

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 H46-H48

Name in latin Aliae morbositates nervi optici et tractuum opticorum

NAME	H7_OPTNEUROTH
CONTROL_EXCLUDE	H7_OPTNERVE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE	H7_OPTNERVNAS\|H7_PAPILLOEDEMA\|H7_OPTATROPHY\|H7_OPTICDISCOTH\|H7_OPTICCHIASM\|H7_VISUALPATHOTH\|H7_VISUALCORTEXOTH\|H7_VISUALPATHNAS
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	H47
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	H47
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Similar endpoints

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List of similar endpoints to Other disorders of optic [2nd] nerve and visual pathways based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1631	948	683
Unadjusted prevalence (%)	0.43	0.45	0.41
Mean age at first event (years)	50.37	47.65	54.16

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	3.47 [1.97, 6.11]	1.6e-5	175
15 years	0.01	1.61 [0.94, 2.75]	8.5e-2	64
5 years	0.00	3.49 [2.32, 5.26]	2.3e-9	50
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_OPTNEUROTH – Other disorders of optic [2nd] nerve and visual pathways
GWS hits:

Survival analyses between endpoints

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Plot

before Other disorders of optic [2nd] nerve and visual pathways
after Other disorders of optic [2nd] nerve and visual pathways

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Table

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Drugs most likely to be purchased after Other disorders of optic [2nd] nerve and visual pathways

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Endpoint not on priority list, no data to show.