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This is a non-core endpoint: only basic statistics are computed.

See these related core endpoints for full statistics:

Disorders of lens


cataract: Partial or complete opacity of the crystalline lens of one or both eyes that decreases visual acuity and eventually results in blindness. Some cataracts appear in infancy or in childhood, but most develop in older individuals. (Sternberg Diagnostic Surgical Pathology, 3rd ed.)

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None


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Check conditions None


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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H25-H28, H28.2*G71.11
Cause of death: ICD-10 H25-H28, H28.2*G71.11

2 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Remove individuals based on genotype QC


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Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 64413 34022 30391
Unadjusted prevalence (%) 17.08 16.14 18.28
Mean age at first event (years) 70.41 69.96 70.90


Not a core endpoint, no data to show.

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Not a core endpoint, no data to show.


Index endpoint: H7_LENS – Disorders of lens
GWS hits:

Survival analyses between endpoints

Not a core endpoint, no data to show.

Drugs most likely to be purchased after Disorders of lens

Endpoint not on priority list, no data to show.