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Glaucoma, exfoliation

DOID EFO MESH SNOMED PheWeb

H7_GLAUCOMA_XFG

glaucoma: Increased pressure in the eyeball due to obstruction of the outflow of aqueous humor.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H40.10
Hospital discharge: ICD-9 3651B
Hospital discharge: ICD-8 37512
Cause of death: ICD-10 H40.10
Cause of death: ICD-9 3651B
Cause of death: ICD-8 37512

2 out of 7 registries used, show all original rules.

3267

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Check minimum number of events None

3267

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Include endpoints None

3267

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Remove individuals based on genotype QC

3125

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H7_GLAUCOMA_XFG

Control definitions

Control exclude H7_GLAUCOMA

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF4
Parent code in ICD-10 H401
Name in latin Glaucoma capsulare [primarium/residuale] cum syndromate exfoliationis

Summary Statistics

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Key figures

All Female Male
Number of individuals 3125 1731 1394
Unadjusted prevalence (%) 0.83 0.82 0.84
Mean age at first event (years) 71.24 70.83 71.74

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.60 [1.18, 2.17] 2.6e-3 708
15 years 0.01 1.09 [0.87, 1.37] 4.5e-1 389
5 years 0.00 1.47 [1.19, 1.82] 3.8e-4 191
1 year 0.00 1.81 [1.29, 2.53] 5.4e-4 45

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_GLAUCOMA_XFG – Glaucoma, exfoliation
GWS hits: 8

Survival analyses between endpoints

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Plot

before Glaucoma, exfoliation
after Glaucoma, exfoliation

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Glaucoma, exfoliation

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Endpoint not on priority list, no data to show.