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Primary angle-closure glaucoma

DOID EFO MESH SNOMED PheWeb

H7_GLAUCCLOSEPRIM

primary angle closure glaucoma: The sudden increase of intraocular pressure, resulting in pain and an abrupt decrease in visual acuity.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H40.2
Hospital discharge: ICD-9 3652
Hospital discharge: ICD-8 37500|37511
Cause of death: ICD-10 H40.2
Cause of death: ICD-9 3652
Cause of death: ICD-8 37500|37511

2 out of 7 registries used, show all original rules.

1249

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Check minimum number of events None

1249

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Include endpoints None

1249

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Remove individuals based on genotype QC

1199

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H7_GLAUCCLOSEPRIM

Control definitions

Control exclude H7_GLAUCOMA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H40
Name in latin Glaucoma congestivum primarium

Summary Statistics

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Key figures

All Female Male
Number of individuals 1199 707 492
Unadjusted prevalence (%) 0.32 0.34 0.30
Mean age at first event (years) 64.15 63.79 64.67

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.32 [0.77, 2.25] 3.1e-1 243
15 years 0.01 0.88 [0.59, 1.31] 5.2e-1 109
5 years 0.00 1.81 [1.29, 2.54] 6.5e-4 65
1 year 0.00 2.47 [1.49, 4.12] 5.0e-4 18

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_GLAUCCLOSEPRIM – Primary angle-closure glaucoma
GWS hits:

Survival analyses between endpoints

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Plot

before Primary angle-closure glaucoma
after Primary angle-closure glaucoma

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Primary angle-closure glaucoma

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Endpoint not on priority list, no data to show.