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Degenerative myopia

DOID EFO MESH PheWeb

H7_DEGENMYOPIA

pathological myopia: ['Excessive axial myopia associated with complications (especially posterior staphyloma and CHOROIDAL NEOVASCULARIZATION) that can lead to BLINDNESS.']

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H44.2
Hospital discharge: ICD-9 3602A
Cause of death: ICD-10 H44.2
Cause of death: ICD-9 3602A

2 out of 7 registries used, show all original rules.

167

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Check minimum number of events None

167

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Include endpoints None

167

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Remove individuals based on genotype QC

161

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H7_DEGENMYOPIA

Control definitions

Control exclude H7_VITREOUS

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H44
Name in latin Myopia degenerativa

Summary Statistics

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Key figures

All Female Male
Number of individuals 161 121 40
Unadjusted prevalence (%) 0.04 0.06 0.02
Mean age at first event (years) 55.41 56.03 53.53

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: H7_DEGENMYOPIA – Degenerative myopia
GWS hits: 1

Survival analyses between endpoints

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Plot

before Degenerative myopia
after Degenerative myopia

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Degenerative myopia

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Endpoint not on priority list, no data to show.