conjunctival degenerations and deposits

H7_CONJUNCTDEGDEPOT

pinguecula: A yellowish thickened lesion on the conjunctiva near the cornea representing a benign degenerative change in the conjunctiva caused by the leakage and deposition of certain blood proteins through the permeable capillaries near the limbus.

Endpoint definition

FinnGen phenotype data

392423 individuals

diagram downward connector

Apply sex-specific rule None

392423

diagram downward connector

Check conditions None

392423

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H11.1
Hospital discharge: ICD-9 3725
Cause of death: ICD-10 H11.1
Cause of death: ICD-9 3725

2 out of 7 registries used, show all original rules.

602

diagram downward connector

Check minimum number of events None

602

diagram downward connector

Include endpoints None

602

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

575

diagram downward connector
H7_CONJUNCTDEGDEPOT

Control definitions

Control exclude H7_CONJUNCTIVA

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H11
Name in latin Degenerationes et deposita conjunctivae

Summary Statistics

Key figures

All Female Male
Number of individuals 575 362 213
Unadjusted prevalence (%) 0.15 0.17 0.13
Mean age at first event (years) 53.05 51.05 56.43

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.08 [0.41, 2.85] 8.8e-1 66
15 years 0.01 0.92 [0.41, 2.05] 8.3e-1 34
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H7_CONJUNCTDEGDEPOT – conjunctival degenerations and deposits
GWS hits:

Survival analyses between endpoints

Plot

before conjunctival degenerations and deposits
after conjunctival degenerations and deposits

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after conjunctival degenerations and deposits

Endpoint not on priority list, no data to show.