Visual impairment including blindness (binocular or monocular)

H7_BLINDANDVISIMPAIRMENT

No definition available.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 H54
Cause of death: ICD-10 H54

2 out of 7 registries used, show all original rules.

1911

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Check minimum number of events None

1911

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Remove individuals based on genotype QC

1882

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H7_BLINDANDVISIMPAIRMENT

Control definitions

Control exclude H7_VISUALDISTBLIND

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 H53-H54
Name in latin Amaurosis et amblyopia

Similar endpoints

List of similar endpoints to Visual impairment including blindness (binocular or monocular) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 1882 1059 823
Unadjusted prevalence (%) 0.50 0.50 0.49
Mean age at first event (years) 61.14 59.45 63.32

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 3.93 [2.59, 5.96] 1.1e-10 367
15 years 0.01 1.40 [0.94, 2.09] 1.0e-1 122
5 years 0.00 3.92 [3.00, 5.12] 1.3e-23 161
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: H7_BLINDANDVISIMPAIRMENT – Visual impairment including blindness (binocular or monocular)
GWS hits: 2

Survival analyses between endpoints

Plot

before Visual impairment including blindness (binocular or monocular)
after Visual impairment including blindness (binocular or monocular)

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Drugs most likely to be purchased after Visual impairment including blindness (binocular or monocular)

Endpoint not on priority list, no data to show.