Gestational diabetes (for exclusion)

GEST_DIABETES

cerebrovascular disorder: A disorder resulting from inadequate blood flow in the vessels that supply the brain. Representative examples include cerebrovascular ischemia, cerebral embolism, and cerebral infarction.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule

Sex only females

219462

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Check conditions None

219462

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 O24.4
Hospital discharge: ICD-9 6488A
Cause of death: ICD-10 O24.4
Cause of death: ICD-9 6488A

2 out of 7 registries used, show all original rules.

13751

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Check minimum number of events None

13751

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Include endpoints None

13751

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Remove individuals based on genotype QC

13039

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GEST_DIABETES

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF4
Parent code in ICD-10 O24
Name in latin Diabetes mellitus in gravidate apparens

Summary Statistics

Key figures

All Female Male
Number of individuals 13039 13039 -
Unadjusted prevalence (%) 3.46 6.19 -
Mean age at first event (years) 31.84 31.84 -

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.07 [0.75, 1.51] 7.1e-1 71
15 years 0.01 0.72 [0.44, 1.17] 1.9e-1 22
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: GEST_DIABETES – Gestational diabetes (for exclusion)
GWS hits: 11

Survival analyses between endpoints

Plot

before Gestational diabetes (for exclusion)
after Gestational diabetes (for exclusion)

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Drugs most likely to be purchased after Gestational diabetes (for exclusion)