Status epilepticus

G6_STATUSEPI

status epilepticus: Status epilepticus is defined as a continuous seizure lasting more than 30 min, or two or more seizures without full recovery of consciousness between any of them.

Endpoint definition

FinnGen phenotype data

392423 individuals

diagram downward connector

Apply sex-specific rule None

392423

diagram downward connector

Check conditions None

392423

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G41
Hospital discharge: ICD-9 3452|3453
Hospital discharge: ICD-8 34520
Cause of death: ICD-10 G41
Cause of death: ICD-9 3452|3453
Cause of death: ICD-8 34520

2 out of 7 registries used, show all original rules.

1065

diagram downward connector

Check minimum number of events None

1065

diagram downward connector

Include endpoints None

1065

diagram downward connector
diagram bullet diagram downward connector

Remove individuals based on genotype QC

1023

diagram downward connector
G6_STATUSEPI

Control definitions

Control exclude G6_EPIPAROX

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G40-G47
Name in latin Status epilepticus

Summary Statistics

Key figures

All Female Male
Number of individuals 1023 450 573
Unadjusted prevalence (%) 0.27 0.21 0.34
Mean age at first event (years) 53.58 49.13 57.08

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.29 21.30 [13.97, 32.46] 6.6e-46 320
15 years 0.03 5.16 [3.31, 8.04] 4.2e-13 70
5 years 0.02 12.23 [8.54, 17.51] 1.5e-42 82
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: G6_STATUSEPI – Status epilepticus
GWS hits:

Survival analyses between endpoints

Plot

before Status epilepticus
after Status epilepticus

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Status epilepticus

Endpoint not on priority list, no data to show.