Inflammatory diseases of the central nervous system

G6_NEUINFL

encephalomyelitis: Inflammation of the brain and the spinal cord.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G00-G09
Cause of death: ICD-10 G00-G09

2 out of 7 registries used, show all original rules.

1699

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Check minimum number of events None

1699

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Remove individuals based on genotype QC

2433

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G6_NEUINFL

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 2433 1314 1119
Unadjusted prevalence (%) 0.65 0.62 0.67
Mean age at first event (years) 41.08 38.95 43.58

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.17 [1.08, 4.33] 2.9e-2 303
15 years 0.01 1.03 [0.60, 1.79] 9.1e-1 82
5 years 0.00 3.47 [2.32, 5.19] 1.4e-9 81
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: G6_NEUINFL – Inflammatory diseases of the central nervous system
GWS hits:

Survival analyses between endpoints

Plot

before Inflammatory diseases of the central nervous system
after Inflammatory diseases of the central nervous system

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Drugs most likely to be purchased after Inflammatory diseases of the central nervous system

Endpoint not on priority list, no data to show.