Other headache syndromes


acute chest syndrome: A vaso-occlusive crisis of the pulmonary vasculature occurring in patients with sickle cell disease. It is characterized by the presence of a new radiodensity on a chest radiograph accompanied by fever, cough, sputum production, dyspnea, or hypoxia.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None


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Check conditions None


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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 G44
Hospital discharge: ICD-8 34601
Cause of death: ICD-10 G44
Cause of death: ICD-8 34601

2 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Include endpoints


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Remove individuals based on genotype QC


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Control definitions

Control exclude G6_EPIPAROX

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G40-G47
Name in latin Alia syndromata cephalalgica

Summary Statistics

Key figures

All Female Male
Number of individuals 15851 11658 4193
Unadjusted prevalence (%) 4.20 5.53 2.52
Mean age at first event (years) 48.44 47.14 52.06


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 1.60 [1.26, 2.04] 1.4e-4 760
15 years 0.01 1.15 [0.92, 1.45] 2.3e-1 390
5 years 0.00 1.69 [1.34, 2.12] 7.1e-6 162
1 year 0.00 3.54 [2.61, 4.79] 2.9e-16 62

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: G6_HEADACHE – Other headache syndromes
GWS hits: 4

Survival analyses between endpoints


before Other headache syndromes
after Other headache syndromes

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Drugs most likely to be purchased after Other headache syndromes

Endpoint not on priority list, no data to show.