Falls/tendency to fall


vestibular disease: Pathological processes of the vestibular labyrinth which contains part of the balancing apparatus. Patients with vestibular diseases show instability and are at risk of frequent falls. [database_cross_reference: MESH:D015837]

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None


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Check conditions None


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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 R29.6, W00-W19
Cause of death: ICD-10 R29.6, W00-W19

2 out of 7 registries used, show all original rules.


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Check minimum number of events None


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Include endpoints None


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Remove individuals based on genotype QC


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Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF3

Summary Statistics

Key figures

All Female Male
Number of individuals 92857 51185 41672
Unadjusted prevalence (%) 24.63 24.28 25.06
Mean age at first event (years) 55.08 54.01 56.40


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.27 [2.96, 3.61] <1e-100 11255
15 years 0.01 1.65 [1.49, 1.82] 1.1e-22 3793
5 years 0.00 4.02 [3.74, 4.32] <1e-100 3967
1 year 0.00 11.74 [10.72, 12.86] <1e-100 2782

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: FALLS – Falls/tendency to fall
GWS hits: 7

Survival analyses between endpoints


before Falls/tendency to fall
after Falls/tendency to fall

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Drugs most likely to be purchased after Falls/tendency to fall

Endpoint not on priority list, no data to show.