Falls/tendency to fall

FALLS

vestibular disease: Pathological processes of the vestibular labyrinth which contains part of the balancing apparatus. Patients with vestibular diseases show instability and are at risk of frequent falls. [database_cross_reference: MESH:D015837]

Endpoint definition

↥

FinnGen phenotype data

392423 individuals

Apply sex-specific rule None

392423

Check conditions None

392423

Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 R29.6, W00-W19

Cause of death: ICD-10 R29.6, W00-W19

2 out of 7 registries used, show all original rules.

96136

Check minimum number of events None

96136

Include endpoints None

96136

Remove individuals based on genotype QC

92857

FALLS

Control definitions

Controls for this endpoint are individuals that are not cases.

Extra metadata

First used in FinnGen datafreeze DF3

NAME	FALLS
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	W[0-1]\|R296
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	W[0-1]\|R296
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Show upset plot detailing case counts by codes

Or the full data table

Similar endpoints

↥

List of similar endpoints to Falls/tendency to fall based on the number of shared cases.

Broader endpoints:

Any ICDMAIN event in hilmo or causes of death

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

↥

Key figures

	All	Female	Male
Number of individuals	92857	51185	41672
Unadjusted prevalence (%)	24.63	24.28	25.06
Mean age at first event (years)	55.08	54.01	56.40

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	3.27 [2.96, 3.61]	<1e-100	11255
15 years	0.01	1.65 [1.49, 1.82]	1.1e-22	3793
5 years	0.00	4.02 [3.74, 4.32]	<1e-100	3967
1 year	0.00	11.74 [10.72, 12.86]	<1e-100	2782

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: FALLS – Falls/tendency to fall
GWS hits: 7

Survival analyses between endpoints

↥

Plot

before Falls/tendency to fall
after Falls/tendency to fall

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Falls/tendency to fall

↥

Endpoint not on priority list, no data to show.

≡ Risteys

R9

R8

R7

R6

R5

R4

R3

Falls/tendency to fall

Endpoint definition

All original rules

Upset plot

Case counts by code for Falls/tendency to fall (FALLS)

Similar endpoints

Summary Statistics

Key figures

Mortality

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Authentication required

Survival analyses between endpoints

Plot

Table

Drugs most likely to be purchased after Falls/tendency to fall