Severe mental retardation

DOID MESH PheWeb

F5_SEVRET

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 F72

Hospital discharge: ICD-9 3181

Hospital discharge: ICD-8 313

Cause of death: ICD-10 F72

Cause of death: ICD-9 3181

Cause of death: ICD-8 313

2 out of 7 registries used, show all original rules.

69

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Check minimum number of events None

69

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Include endpoints None

69

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Remove individuals based on genotype QC

66

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F5_SEVRET

Control definitions

Control exclude F5_MENTRET

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 F70-F79

Name in latin Retardatio mentalis gravis

NAME	F5_SEVRET
CONTROL_EXCLUDE	F5_MENTRET
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	F72
HD_ICD_9	3181
HD_ICD_8	313
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	F72
COD_ICD_9	3181
COD_ICD_8	313
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

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Similar endpoints

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List of similar endpoints to Severe mental retardation based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	66	28	38
Unadjusted prevalence (%)	0.02	0.01	0.02
Mean age at first event (years)	28.71	21.99	33.67

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: F5_SEVRET – Severe mental retardation
GWS hits:

Survival analyses between endpoints

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Not a core endpoint, no data to show.

Drugs most likely to be purchased after Severe mental retardation

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Endpoint not on priority list, no data to show.