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Schizoaffective disorder

DOID EFO MESH PheWeb

F5_SCHIZOAFF

schizoaffective disorder: A disorder in which the individual suffers from both symptoms that qualify as schizophrenia and symptoms that qualify as a mood disorder (e.g., depression or bipolar disorder) for a substantial portion (but not all) of the active period of the illness; for the remainder of the active period of the illness, the individual suffers from delusions or hallucinations in the absence of prominent mood symptoms.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 F25
Hospital discharge: ICD-9 2957
Hospital discharge: ICD-8 2957
Cause of death: ICD-10 F25
Cause of death: ICD-9 2957
Cause of death: ICD-8 2957

2 out of 7 registries used, show all original rules.

2866

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Check minimum number of events None

2866

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Include endpoints None

2866

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Remove individuals based on genotype QC

2742

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F5_SCHIZOAFF

Control definitions

Control exclude F5_SCHIZO

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F20-F29
Name in latin Perturbationes schizoaffectivae

Summary Statistics

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Key figures

All Female Male
Number of individuals 2742 1613 1129
Unadjusted prevalence (%) 0.73 0.77 0.68
Mean age at first event (years) 37.46 37.51 37.39

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.70 [1.70, 4.30] 2.6e-5 188
15 years 0.01 2.04 [1.35, 3.08] 7.5e-4 76
5 years 0.00 3.38 [2.15, 5.32] 1.4e-7 30
1 year 0.00 8.56 [4.69, 15.61] 2.5e-12 14

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: F5_SCHIZOAFF – Schizoaffective disorder
GWS hits:

Survival analyses between endpoints

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Plot

before Schizoaffective disorder
after Schizoaffective disorder

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Schizoaffective disorder

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Endpoint not on priority list, no data to show.