Other and unspecified nonorganic psychotic disorders

F5_PSYCHOTH

psychosis: An abnormal condition of the mind that involves a loss of contact with reality. People experiencing psychosis may exhibit personality changes and thought disorder. Depending on its severity, this may be accompanied by unusual or bizarre behavior, as well as difficulty with social interaction and impairment in carrying out daily life activities.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 F28, F29
Hospital discharge: ICD-9 2989
Hospital discharge: ICD-8 29999
Cause of death: ICD-10 F28, F29
Cause of death: ICD-9 2989
Cause of death: ICD-8 29999

2 out of 7 registries used, show all original rules.

7901

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Check minimum number of events None

7901

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Include endpoints None

7901

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Remove individuals based on genotype QC

7508

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F5_PSYCHOTH

Control definitions

Control exclude F5_SCHIZO

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 7508 3982 3526
Unadjusted prevalence (%) 1.99 1.89 2.12
Mean age at first event (years) 34.80 35.61 33.89

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 4.20 [3.36, 5.27] 1.1e-35 437
15 years 0.02 2.74 [2.19, 3.44] 2.2e-18 170
5 years 0.01 4.79 [3.68, 6.24] 3.0e-31 95
1 year 0.00 10.73 [7.55, 15.25] 5.6e-40 43

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: F5_PSYCHOTH – Other and unspecified nonorganic psychotic disorders
GWS hits:

Survival analyses between endpoints

Plot

before Other and unspecified nonorganic psychotic disorders
after Other and unspecified nonorganic psychotic disorders

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Drugs most likely to be purchased after Other and unspecified nonorganic psychotic disorders

Endpoint not on priority list, no data to show.