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Generalized anxiety disorder

DOID EFO MESH SNOMED PheWeb

F5_GAD

generalized anxiety disorder: An anxiety disorder that is characterized by long-lasting anxiety that is not focused on any one object or situation.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 F41.1
Hospital discharge: ICD-9 3000C
Cause of death: ICD-10 F41.1
Cause of death: ICD-9 3000C

2 out of 7 registries used, show all original rules.

4838

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Check minimum number of events None

4838

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Include endpoints None

4838

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Remove individuals based on genotype QC

4666

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F5_GAD

Control definitions

Control exclude F5_NEUROTIC

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2
Parent code in ICD-10 F41
Name in latin Perturbatio anxifera generalisata

Summary Statistics

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Key figures

All Female Male
Number of individuals 4666 3367 1299
Unadjusted prevalence (%) 1.24 1.60 0.78
Mean age at first event (years) 40.40 39.89 41.71

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 4.42 [2.87, 6.80] 1.4e-11 139
15 years 0.02 2.39 [1.54, 3.72] 1.0e-4 58
5 years 0.00 4.01 [2.65, 6.07] 4.4e-11 33
1 year 0.00 11.49 [6.77, 19.50] 1.4e-19 19

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: F5_GAD – Generalized anxiety disorder
GWS hits: 1

Survival analyses between endpoints

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Plot

before Generalized anxiety disorder
after Generalized anxiety disorder

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Generalized anxiety disorder

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Endpoint not on priority list, no data to show.