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Recurrent or chronic depression

PheWeb

F5_DEPRESSION_RECURRENT

No definition available.

Endpoint definition

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FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions

not (F5_SCHIZO
or F5_SCHIZOAFF
or F5_BIPO

373914

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Check pre-conditions, main-only, mode, registry filters

Primary healthcare outpatient: ICD-10: F33
Hospital Discharge: ICD-10 F33
Cause of death: ICD-10 F33

3 out of 7 registries used, show all original rules.

17893

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Check minimum number of events None

17893

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Include endpoints

17893

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Remove individuals based on genotype QC

17227

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F5_DEPRESSION_RECURRENT

Control definitions

Control exclude F5_PSYCH, ANTIDEPRESSANTS

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF9

Summary Statistics

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Key figures

All Female Male
Number of individuals 17227 12825 4402
Unadjusted prevalence (%) 4.57 6.08 2.65
Mean age at first event (years) 44.31 43.17 47.61

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.25 [1.60, 3.16] 3.6e-6 534
15 years 0.01 1.50 [1.11, 2.01] 7.7e-3 240
5 years 0.00 3.59 [2.74, 4.69] 1.3e-20 172
1 year 0.00 6.10 [4.33, 8.61] 6.3e-25 56

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: F5_DEPRESSION_RECURRENT – Recurrent or chronic depression
GWS hits: 8

Survival analyses between endpoints

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Plot

before Recurrent or chronic depression
after Recurrent or chronic depression

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Recurrent or chronic depression

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Endpoint not on priority list, no data to show.