Anorexia (incl.atypical)

F5_ANOREX

anorexia nervosa: A disorder most often seen in adolescent females characterized by a refusal to maintain a minimally normal body weight, an intense fear of gaining weight, a disturbance in body image, and, in postmenarcheal females, the development of amenorrhea.

Endpoint definition

FinnGen phenotype data

392423 individuals

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Apply sex-specific rule None

392423

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Check conditions None

392423

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Check pre-conditions, main-only, mode, registry filters

Hospital Discharge: ICD-10 F50.0, F50.1
Hospital discharge: ICD-9 7830A|3071A
Hospital discharge: ICD-8 784
Cause of death: ICD-10 F50.0, F50.1
Cause of death: ICD-9 7830A|3071A
Cause of death: ICD-8 784

2 out of 7 registries used, show all original rules.

1965

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Check minimum number of events None

1965

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Include endpoints None

1965

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Remove individuals based on genotype QC

1897

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F5_ANOREX

Control definitions

Control exclude F5_BEHAVE

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 1897 1494 403
Unadjusted prevalence (%) 0.50 0.71 0.24
Mean age at first event (years) 23.26 21.96 28.10

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.04 2.54 [1.62, 4.01] 5.6e-5 122
15 years 0.01 1.28 [0.85, 1.93] 2.4e-1 42
5 years 0.00 2.67 [1.72, 4.14] 1.2e-5 27
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: F5_ANOREX – Anorexia (incl.atypical)
GWS hits:

Survival analyses between endpoints

Plot

before Anorexia (incl.atypical)
after Anorexia (incl.atypical)

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Drugs most likely to be purchased after Anorexia (incl.atypical)

Endpoint not on priority list, no data to show.